... the first woman to make a substantial contribution to the development of mathematics.Now the first question that it is necessary to tackle is whether Pandrosion was a man or a woman. This may seem rather a surprising question to have to answer but it has to be considered since early translations of Pappus's works have presented her as a man. Later work, however, has convincingly shown that this was an error and it now appears to be widely accepted by historians that Pandrosion was a woman. We present here a short extract from  where the problem is clearly shown and its resolution is well argued; see THIS LINK.
Since nothing seems to be known of Pandrosion other than the references by Pappus, we present a short extract from  where essentially all that is known about Pandrosion is stated. The reasons why it is believed that Pappus tried to show Pandrosion as an incompetent mathematical teacher are also clearly argued; see THIS LINK.
There still remains the question of whether Pandrosion made "a substantial contribution to the development of mathematics." As no writings by Pandrosion are extant, or are even referred by later Greek writers, this is in many ways an impossible question to answer. That no writings by Pandrosion come down to us today is, perhaps, not surprising since none of Hypatia's writings are known in the original. It is suggested that Pandrosion may have suffered from the unfair attack that Pappus made on her competence and this could well explain why later authors chose not to refer to her work. Certainly this all presents fascinating question for pondering although it would seem that no definitive answers will ever be reached.
Article by: J J O'Connor and E F Robertson